Bromopride is an antiemetic and prokinetic medicine indicated for the treatment of nausea and vomiting or changes in gastrointestinal movements, which works by blocking the effect of dopamine, a type of neurotransmitter with action in the gastrointestinal system and brain, which causes nausea and vomiting related to surgeries or gastroesophageal reflux, for example.
This medicine can be found in pharmacies or drugstores in the form of capsules, tablets or drops, with the trade name Digesan, in generic form with the name Bromopride or with similar names Plamet or Fagico, for example. In addition, bromopride can also be found in the form of an injection for application into the muscle or injection directly into a vein, and is only used in hospitals, under the supervision of a healthcare professional.
Bromopride can be used by adults or children over 1 year of age, and should be used with medical advice and guidance.
What is it for
Bromopride is indicated for the treatment or prevention of nausea and vomiting, changes in stomach and intestinal movements, and to alleviate symptoms caused by gastroesophageal reflux, as it acts by blocking the effect of dopamine in the brain and gastrointestinal system, in addition to increasing emptying. gastric and intestinal transit. Know how to identify the symptoms of gastroesophageal reflux.
Furthermore, bromopride can also be used during radiological examinations.
How to drink
How bromopride is used depends on the presentation of the medicine and includes:
1. Bromopride pediatric drops 4 mg/mL
Bromopride pediatric drops contain 4 mg of bromopride in each 1 mL of solution, sold in a 20 mL bottle, and must be taken orally.
The recommended dose for children over 1 year of age is 1 to 2 drops for each kg of body weight, up to three times a day, as advised by the pediatrician.
2. Bromopride oral solution 1 mg/mL
Bromopride oral solution contains 1 mg of bromopride for every 1 mL of solution, and is sold in 120 mL bottles.
Doses must be taken orally and vary according to age:
- Adults: The recommended dose for adults is 10 mL of the oral solution, which corresponds to 10 mg of bromopride, taken every 8 or 12 hours, according to the doctor’s instructions. The maximum dose per day should not be greater than 60 mg;
- Children over 1 year old: the recommended dose for children is 0.5 to 1 mg for each kg of body weight, per day, divided into 3 daily doses.
The duration of treatment with bromopride oral solution must be advised by the doctor on an individual basis.
3. Bromopride tablet or 10 mg capsules
Bromopride, in the form of 10 mg tablets or capsules, must be taken orally and is only recommended for adults.
The recommended dose is 1 tablet or capsule of 10 mg every 8 or 12 hours, according to medical advice. The maximum dose per day should not be more than 60 mg.
4. Injectable bromopride 10 mg/2 mL
Injectable bromopride 10 mg/2mL must be applied directly to the vein or muscle of the arm or buttocks, by a doctor, nurse or trained health professional, and the dose must be determined by the doctor according to the disease to be treated.
Generally, the recommended doses for use of injectable bromopride are:
- Adults: the recommended intravenous or intramuscular dose is 1 to 2 ampoules per day;
- Children over 1 year old: the recommended dose is 0.5 to 1 mg for each kg of body weight, per day, intramuscularly or intravenously.
These doses can be changed by the doctor depending on the severity of nausea and vomiting or gastroesophageal reflux symptoms.
Possible side effects
The most common side effects that may occur during treatment with bromopride are restlessness, drowsiness, excessive tiredness, decreased strength or exhaustion.
Although it is rarer, tremors, muscle contractions, difficulty walking, slowing of movements, agitation, convulsions, insomnia, headache, dizziness, nausea, excessive or inadequate milk production, breast enlargement in men, formation of spots on the skin and intestinal disorders.
Additionally, bromopride can cause serious allergic reactions that require immediate medical attention. Therefore, you should stop treatment and seek the nearest emergency room if you experience symptoms such as difficulty breathing, chest pain, a feeling of a closed throat, swelling in the mouth, tongue or face, or hives. Know how to identify the symptoms of a serious allergic reaction.
In the case of injectable bromopride, as it is used in hospitals in the event of an allergic reaction, treatment is immediate.
Who shouldn’t use
Bromopride should not be used by children under 1 year of age, by pregnant or breastfeeding women, or by people who have gastrointestinal bleeding, obstruction or perforation, epilepsy or pheochromocytoma.
Furthermore, this medicine should not be used by people who are allergic to bromopride or who are being treated with other antiemetics such as metoclopramide, ondansetron, or medicines such as haloperidol, chlorpromazine, risperidone, cinnarizine or fluoxetine, citalopram or sertraline, for example.
It is important to inform the doctor of all the medicines the person uses, as bromopride can reduce the effect of digoxin used to treat heart disease, or increase the action of paracetamol, tetracycline or levodopa, which can cause intoxication or serious side effects.
Source: www.tuasaude.com